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transfer RNA (tRNA)

The class of small RNA molecules that transfer amino acids to the ribosome during protein synthesis. Transfer RNA molecules are folded into a 'clover-leaf' secondary structure by intrastrand base pairing. The anticodon loop contains a nucleotide-triplet complementary to a specific codon within the mRNA molecule. Each tRNA is 'charged' with the correct amino acid molecule, via its 3´ adenosine moiety, by an enzyme called aminoacyl-tRNA synthetase.

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