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bradykinin

1) A nonapeptide messenger that is enzymatically produced from kallidin in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from mast cells during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.

2) A nonapeptide kinin and neuropeptide involved in blood pressure regulation and pain receptor stimulation.

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  • Max Bryant
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