It aired from January 28, 2007 to January 20, 2008 and ran for 49 episodes.

Ryotaro Nogami is a young man with incredibly bad luck who in one day is possessed by a mysterious creature known as an Imagin and discovers the Rider Pass, a device that enables him to transform into Kamen Rider Den-O. When the Rider Pass's owner Hana approaches him, they are attacked by another Imagin, one who come from a possible future to 2007 who grant wishes to weakwilled humans in order to go back further in time to change the past to favor the Imagin's own future. Hana has Ryotaro transform, and the Imagin who possessed him takes pity on him and offers to take over his body and fight in his place. Ryotaro joins Hana, the Imagin Momotaros, and the crew of the DenLiner, which soon includes other Imagin who open contracts with Ryotaro, to protect the flow of time so the future of humanity remains as the one true future.