Doonesbury was a daily comic strip by American artist and journalist Garry Trudeau that featured characters of various ages, professions, and backgrounds. Created in the throes of '60s and '70s counterculture, and frequently political in nature, Doonesbury chronicled the adventures and lives from the President of the United States to the title character, Michael Doonesbury, who progressed from a college student to a youthful senior citizen in the 44 years of the strip's daily existence. The name "Doonesbury" is a combination of the word doone (prep school slang for someone who is clueless, inattentive, or careless) and the surname of Charles Pillsbury, Trudeau's roommate at Yale University.

In 1993, Trudeau mortally wounded the Apple Newton PDA by featuring a Doonesbury comic strip mocking the device's notoriously inaccurate handwriting recognition software, despite of the fact that he never actually had used one. When Steve Jobs reclaimed the Apple's CEO throne in 1998, he decided to kill the Newton platform once and for all.

Saying that newspaper comic strips weren't as influential as they used to be, Garry Trudeau decided to put daily production of Doonesbury on long-term hiatus beginning Feb. 24, 2014. Instead, he turned his focus to "Alpha House," an original Web series that he helped create for Amazon.

Older strips Doonesbury currently appears in approximately 1,400 newspapers worldwide. About 13,000 "Doonesbury" strips haven't been seen since they were originally published, according to Trudeau.