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The process by which progeny derive a combination of genes different from that of either parent. In higher organisms, this can occur by crossing over.
See also: crossing over, mutation.
Industry:Biology
A DNA base sequence that controls gene expression..
Industry:Biology
A gene located in a chromosome region suspected of being involved in a disease.
See also: positional cloning, protein.
Industry:Biology
A chromosome abnormality in which a piece of DNA is incorporated into a gene and thereby disrupts the gene's normal function.
See also: chromosome, DNA, gene, mutation.
Industry:Biology
Gel-filled silica capillaries used to separate fragments for DNA sequencing. The small diameter of the capillaries permit the application of higher electric fields, providing high speed, high throughput separations that are significantly faster than traditional slab gels..
Industry:Biology
Degree of molecular detail on a physical map of DNA, ranging from low to high..
Industry:Biology
One crossover event inhibits the chances of another crossover event. Also known as positive interference. Negative interference increases the chance of a second crossover.
See also: crossing over.
Industry:Biology
The period in the cell cycle when DNA is replicated in the nucleus; followed by mitosis..
Industry:Biology
The presence of retroviral vectors, such as some viruses, which use their recombinant DNA to insert their genetic material into the chromosomes of the host's cells. The virus is then propogated by the host cell..
Industry:Biology