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A widely used method of determining the order of bases in DNA.
See also: sequencing, shotgun sequencing.
Industry:Biology
Where alleles occur together more often than can be accounted for by chance. Indicates that the two alleles are physically close on the DNA strand.
See also: Mendelian inheritance.
Industry:Biology
The self-replicating genetic structure of cells containing the cellular DNA that bears in its nucleotide sequence the linear array of genes. In prokaryotes, chromosomal DNA is circular, and the entire genome is carried on one chromosome. Eukaryotic genomes consist of a number of chromosomes whose DNA is associated with different kinds of proteins..
Industry:Biology
A chromosomal segment that branches off from the rest of the chromosome but is still connected by a thin filament or stalk..
Industry:Biology
A map of the relative positions of genetic loci on a chromosome, determined on the basis of how often the loci are inherited together. Distance is measured in centimorgans (cM)..
Industry:Biology
Attachment of certain fluorescent dyes to targeted parts of the chromosome. Used as a diagnositic for particular diseases, e.g. types of leukemia..
Industry:Biology
In genomic mapping, a series of contigs that are in the right order but not necessarily connected in one continuous stretch of sequence..
Industry:Biology
Determination of the original position (locus) of a gene or other marker on a chromosome..
Industry:Biology
The normal biological process whereby the two pieces of a chromosome pair are separated during meiosis and randomly distributed to the germ cells..
Industry:Biology
